Let’s Talk Terpenes – Cymene

This is the 20th installment in our weekly series, “Let’s Talk Terpenes,” published every Monday. For more information, read the introduction to this series, “Let’s Talk Terpenes: A Guide For Medical Marijuana Patients.”

Today, our focus is on cymene, also referred to as p-cymene. This compound is considered a secondary monoterpene due to the low concentrations in which it is found in cannabis. The terpene is found in over 100 plants and 200 foods, most commonly in thyme and in cumin as well as coriander, eucalyptus, cilantro, and oregano. Strains that commonly contain cymene exhibit an earthy or musty aroma and include Bakerstreet, Mango Haze, Lemon Skunk and Moon.

Those utilizing strains high in this terpene often report a sense of calm as well as anxiety and relief, which leads us further into the studies of the therapeutic and medicinal uses of this beneficial molecule.

Researchers and scientists are continually searching for new ways to alleviate and/or eliminate pain without the negative side effects associated with pharmaceutical pain medicines. A study published in 2012 found that cymene significantly increased the amount of time it took for mice to feel the pain caused by heat and inflammation. Another study published in 2015 discovered similar results, theorizing that cymene is able to significantly reduce inflammation and pain by regulating the opioid system. These results, while comparable to the 2012 study, make further progress by attempting to determine the cause of relief. Research shows that Medical Marijuana patients seeking a strain for pain relief should be on the lookout for those high in cymene. 

While it is obvious that cymene has powerful medicinal effects, more research is needed to determine its mechanisms of action as well as its potential in replacing pharmaceutical pain-relievers.

Cymene has been shown to prolong the duration of the neurotransmitter Acetylcholine, increasing memory and attentiveness. Furthermore, this neurotransmitter can lower blood pressure by inhibiting cardiac muscle to contract.

This terpene may inspire more motivation. A modest amount is helpful to those who suffer from ADHD or mood disorders. So far, it has proved to be beneficial but much more research is necessary to provide hard data that proves conclusively that cymene is a viable treatment option.

Research has also demonstrated the antibacterial properties of cymene. One study revealed cymene to be effective against E.coli in contaminated unpasteurized apple juice. Another study showed cymene’s antifungal properties to surge when actively fighting pathogens alongside other terpenes, such as terpineol and linalool. This synergistic combination is otherwise known as the Entourage Effect.

Scientists are also researching how antimicrobial packaging made of waxy substances like cymene could be a new way of protecting fruits and vegetables during shipping. Rather than using plastic or other more expensive packages, the terpene’s wax-like characteristics and antimicrobial and antifungal qualities will keep foods safer in a more environmentally friendly manner.

Understanding individual terpene characteristics can play a key factor in selecting the ideal strain. Whether inhaled or used aromatically or topically, cymene can be a key component in the broad spectrum of terpenes and cannabinoids that maximize the therapeutic effects cannabis may provide. Feel free to email us to assist with any questions you may have.